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New H5N1 bird flu study just dropped

It’s brutal.

This is a real-world proof-of-concept for mammalian adaptation.

It shows H5N1 doesn’t need years or massive jumps to evolve.

It can do it in a single host.

That makes spillover-to-sustained-transmission far more plausible than officials have let on.

Researchers found 100% lethality and 100% transmission in mice when exposed to an H5N1 strain with the E627K mutation *after just one passage*

Experiment 1 (4 infected mice to 1 uninfected):

100% transmission to the uninfected mouse.

100% of mice died.

The E627K mutation went from 4% to nearly 100% in the lungs and brains within 6 days.

That newly dominant version was then successfully transmitted.

Experiment 2 (1 infected mouse to 1 uninfected):

50% transmission.

All infected mice still died.

Again, the E627K mutation rapidly fixated

H5N1 adapts in real-time inside mammals.

It becomes more mammal-friendly and more lethal in just days.

The PB2-E627K mutation is so strongly favored in mammals that it quickly dominates even when rare.

Queensland Health has issued an urgent alert after a man arrived in Australia from Africa carrying a new strain of monkeypox, with 59 people exposed so far.

Sigade Aafrika katku (SAK) nakatumine tuvastati Tartu vallas, Porkna talus. Seafarmile on põllumajandus- ja toiduameti (PTA) teatel seatud kitsendused. Farmist ei tohi sigu välja ega sisse tuua, samuti on taudipunkti likvideerimiseni piiratud inimeste ja transpordi liikumine.

Since July, more than 7,000 cases of the mosquito-borne chikungunya virus have been reported in China's Guangdong province. Measures similar to those used during the Covid-19 pandemic have been taken.

Masked soldiers are spraying parks and streets with insecticide, and drones have been deployed to detect mosquito breeding sites.

Most people bitten by an infected mosquito develop symptoms within 3-7 days, and include fever, muscle and joint pain and swelling, rashes, and headaches.

In Colorado, a virus is causing rabbits to develop strange, antler-like growths on their heads.

Kumb on tõenäolisem, kas järgmine kriis on sõda või uus pandeemia?

Kindlasti pean tõenäolisemaks uue pandeemia toimumist. Praegu on näha ohuna linnugrippi. Nakatumine kasvab, on olnud üksikuid juhte, kus linnugripp on üle kandunud inimesele. Jälgime, kas hakkab kanduma inimeselt inimesele. See oleks pandeemiline olukord. Varume juba linnugripivaktsiine läbi lepingute, mis annavad vajadusel õiguse vaktsiin välja osta. Peamiselt on oht neil, kes töötavad vahetult lindudega.

Oleme selleks valmis?

Praeguste teadmiste kohaselt jah, vaktsiinid on olemas, aga lähiaastail pandeemiat ilmselt ei tule. Euroopa Liit ostab vaktsiinide tootmise õiguse siis, kui neid on rohkem vaja. Peale linnugripi jälgime ka malaariat. Kui kliima soojeneb, muutub Eesti elukeskkond sobivamaks erinevatele putukatele ja parasiitidele, kes kannavad edasi haiguseid. Mõned tuntud haigustekitajad, nagu Lääne-Niiluse palavik, Dengue viirus ja isegi malaaria, võivad üha enam meie poole liikuda.

South Korea CDC Announces A 19-day, Nationwide, Mock-Training Exercise to Prepare for Zoonotic Influenza

- Täistsükli kiirreageerimissüsteemi kohapealne kontroll alates loomade (linnugripi) diagnostiliste reagentide hankimisest kuni inimeste nakkuste testimiseni.

- Avaliku ja erasektori koostöö tugevdamine 33 organisatsiooni, sealhulgas Korea haiguste tõrje ja ennetamise ameti, toidu- ja ravimiohutuse ministeeriumi, kohalike omavalitsuste ja erasektori testimisasutuste osalusel.

Korea haiguste tõrje ja ennetamise amet (KDCA) (direktor Seung-Kwan Lim) viib esmaspäevast, 1. septembrist kuni reedeni, 19. septembrini läbi üleriigilise simuleeritud õppuse kiirreageerimissüsteemi diagnostilise testimise jaoks, et valmistuda loomade (linnugripi) nakkuse puhanguks inimestel.

Madis Reivik kirjutas: ↑04 Sept, 2025 7:41 Kodumailt ka lollide saavutusi
https://www.postimees.ee/8317200/jahime ... -tee-keegi

Madis Reivik kirjutas: ↑04 Sept, 2025 7:33 Punktivõit idiootidele

https://www.cnbc.com/2025/09/03/florida ... 88dce1647f

The World Organization for Animal Health (WOAH) announces the outbreak of a highly contagious form of H5N1 Bird Flu in Iran

Iran reports a new outbreak of highly contagious H5N1 bird flu in the north of the country, the World Organisation for Animal Health (WOAH) has confirmed.
Officials say 10 birds died in a flock of 90, and the rest were culled to stop the virus from spreading.

The H5N1 strain known as bird flu has been spreading globally, killing millions of poultry over the past few years.
It has caused major disruptions to egg and meat supplies and driven up food prices in many countries.

Iran’s outbreak is part of a larger wave of avian flu cases affecting farms and wild birds worldwide. Experts say outbreaks often start when migratory birds carry the virus across borders and infect domestic flocks.

The risk to people is still very low, according to the World Health Organization.
Most human infections only happen after close contact with sick birds, and there’s no evidence of easy human-to-human spread. Still, scientists are watching closely if the virus mutates.